Experimental therapeutic investigations with 1-(morpholinomethyl)-4-phthalimido-piperidindione-2,6 on dimethylbenzanthracene-induced tumors of Sprague-Dawley rats.
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منابع مشابه
The following is a report on our long-term observations in DMBA-induced mammary tumors in Sprague-Dawley rats
The survival time of rats with 7 , l2-dimethylbenzanthra cene-induced tumors is significantly increased by treatment with the combination of the cyclic imide l-(morpholino methyl)-4-phthalimido-piperidindione-2 , 6 and drostanolone propionate (2a-methyl dihydrotestosterone propionate). In long-term treatment the antitumor activity, determined by the number of the tumor centers, is likewise sign...
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in this study,14 female sprague-dawley rats 55 days old were randomly divided into two control and experimental groups.2ml of 7,12-dimethylbenz{a} anthracene (DMBA) solution(20 mg of DMBA dissolved in 2 ml of corn oil) and 2 ml corn oil was eaten to each animal of test and control group respectively.tumor development was examined by milk line palpation once every week.during 3-5 months followin...
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Background & Objective: Apium graveolens has antioxidant property because of its flavonoid compounds. In the present study, we investigated the hepatoprotective effects of hydroalcoholic extract of Apium graveolens in Sprague Dawley male rats treated with carbon tetrachloride (CCl4). Materials & Methods: In this study, 48 rats (weighted 180-200 gram) were divided into six groups each having e...
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High levels of anti-phosphatidylinositol (Ptdlns) autoantibodies (autoAb) have been previously described in sera of cancer patients and in plasma of dimethylbenzanthracene-treated female Sprague-Dawley rats. The presence of anti-Ptdlns autoAb was tested in a model of highly malignant sarcomas induced by a single dose of benzo(a)pyrene |B(a)P] diluted in sesame oil and injected in female Sprague...
متن کاملEffects of irradiated glucose solutions on DMBA-induced tumors in rats.
lisis is a study of the effects of irradiated glucose-saline solutions (~° Co, 10 R at a dose rate of 1.7 X 106 R/h) on tumors induced by the intravenous injection of dimethylbenzanthracene (DMBA) in female Sprague-Dawley rats. Each animal received 10 cc intraperitoneal injections of the irradiated solution spaced over 17 days. As a control two groups of tumor beariRg animals were used: bne rec...
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عنوان ژورنال:
- Cancer research
دوره 29 6 شماره
صفحات -
تاریخ انتشار 1969